By Thomas Blackburn
This monograph was once assembled to honor Professor Norman Bowery and his paintings at the 30th anniversary of his discovery of the GABAB receptor. within the current quantity, top neuroscientists from academia and supply a standpoint of present examine, either simple and translational, within the discovery of substances performing at the GABAB receptor. the themes coated offer a accomplished overview of the sector and the present kingdom of analysis during this quarter. integrated are chapters at the chemistry of GABAB agonists and antagonists, at the genetics and molecular composition of the location, its rules and trafficking, and its position in controlling mobile, autonomic, and behavioral functionality. There also are chapters describing the aptitude scientific application of substances regulating GABAB task receptor in the components of high blood pressure, gastroesophageal reflux disorder, Down syndrome, melancholy, and substance abuse.
The details contained during this textual content may be of specific curiosity to neuroscientists ordinarily and to neuropharmacologists particularly.
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